Firefighters were called to the 3800 block of West 18th street around 3:30 Sunday morning for reports of a building on fire.
According to Little Rock Fire Department Captain Jason Weaver, when crews arrived they found light smoke coming from First Baptist Church Highland Park.
When firefighters entered the building, they began to battle a fire on the first floor but backed out after hearing it in the upper floors.
Weaver says fire had broken through the gables and flames were shooting out of the building.
Crews went into defensive mode and continued to fight the fire from outside.
Weaver says the church building is a total loss.
Fire marshals are investigating the cause of the blaze.